Department of Medicine, Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, SC 29425, USA.
Drug Alcohol Depend. 2011 May 1;115(1-2):9-15. doi: 10.1016/j.drugalcdep.2010.09.023. Epub 2010 Dec 9.
Illicit methamphetamine use has risen dramatically over the last decade. We sought to examine methamphetamine use among individuals presenting for drug treatment in South Carolina, USA, to assess trends over time, correlates of methamphetamine use, and the relationship between methamphetamine use and functional/behavioral problems.
Data from 2000 to 2005 were obtained from a state-wide network of substance abuse clinics. We examined time trends, and compared sociodemographic characteristics and problems with daily functioning (Axis IV and Axis V disorders) of methamphetamine users vs. other drug users.
Of 235,415 individuals presenting or being admitted to a clinic, 3526 reported illicit methamphetamine use. The prevalence of methamphetamine use as a presenting problem increased dramatically across the six-year period, especially in the rural Upstate region (0.4-6.1%). In comparison to other drug users presenting or admitted to treatment during this same time period, methamphetamine users were more likely to be female, between 20 and 40 years old, and non-Hispanic white ethnicity. In addition, more methamphetamine users had occupational (49% vs. 43%, p<0.001) or economic problems (41% vs. 35%, p<0.001), and problems with their primary support group (58% vs. 54%, p<0.05). However, the prevalence of Axis IV and Axis V problems were not statistically different between the two groups.
The rapid escalation of methamphetamine use in South Carolina and elsewhere highlights the need for longitudinal studies to better understand the etiology and characteristics associated with methamphetamine uptake and addiction, and to develop the knowledge base required for more effective prevention and treatment.
在过去十年中,非法甲基苯丙胺的使用急剧增加。我们试图研究美国南卡罗来纳州接受药物治疗的个体中甲基苯丙胺的使用情况,以评估随时间的趋势、与甲基苯丙胺使用相关的因素以及甲基苯丙胺使用与功能/行为问题之间的关系。
我们从全州范围的药物滥用诊所网络获取了 2000 年至 2005 年的数据。我们检查了时间趋势,并比较了甲基苯丙胺使用者与其他药物使用者的社会人口统计学特征和日常功能障碍(第四轴和第五轴障碍)问题。
在 235415 名就诊或住院的个体中,有 3526 名报告了非法使用甲基苯丙胺。在六年期间,作为主要问题出现的甲基苯丙胺使用的流行率急剧增加,尤其是在农村上州地区(0.4-6.1%)。与同期接受治疗的其他药物使用者相比,甲基苯丙胺使用者更有可能是女性、20 至 40 岁、非西班牙裔白人。此外,更多的甲基苯丙胺使用者存在职业(49%比 43%,p<0.001)或经济问题(41%比 35%,p<0.001),以及主要支持群体问题(58%比 54%,p<0.05)。然而,两组之间第四轴和第五轴问题的患病率没有统计学差异。
南卡罗来纳州和其他地方甲基苯丙胺使用的迅速增加强调了需要进行纵向研究,以更好地了解与甲基苯丙胺摄入和成瘾相关的病因和特征,并为更有效的预防和治疗开发所需的知识基础。