[Studies on pyridazinone derivatives. XV. Oxidative reactions and antibacterial antifungal activity of sulfur derivatives of pyridazinone].

Oxidative reactions of o-nitrophenylthio substituted 2-phenyl-3(2H)-pyridazinones (3, 4, 13) with hydrogen peroxide were examined and o-nitrophenylsulfinyl compounds (5, 7, 14) and o-nitrophenylsulfonyl compound (6) were obtained. As the results of antibacterial antifungal screening tests in vitro, 3, 5 and 6 revealed strong antitrichophyton activities.