5-氯-6-苯基哒嗪-3(2H)-酮衍生物的合成及其抗真菌活性
Synthesis and antifungal activity of 5-chloro-6-phenylpyridazin-3(2H)-one derivatives.
作者信息
Wu Jian, Song Baoan, Chen Hongjun, Bhadury Pinaki, Hu Deyu
机构信息
Key Laboratory of Green Pesticide and Agriculture Bioengineering, Ministry of Education, Research and Development Center for Fine Chemicals, Guizhou University, Guiyang 550025, China.
出版信息
Molecules. 2009 Sep 18;14(9):3676-87. doi: 10.3390/molecules14093676.
An effective method has been developed for the preparation under mild conditions of novel pyridazine derivatives from the easily accessible starting materials mucochloric acid and benzene. All the synthesized compounds were fully characterized and some of them displayed good antifungal activities against G. zeae, F. oxysporum and C. mandshurica in preliminary antifungal activity tests.
已开发出一种有效方法，可在温和条件下由易于获得的原料粘氯酸和苯制备新型哒嗪衍生物。所有合成的化合物均得到充分表征，其中一些在初步抗真菌活性测试中对玉米赤霉、尖孢镰刀菌和东北炭疽菌显示出良好的抗真菌活性。
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