Romagnoli S E, Camillo F, Cela M, Johnston S D, Grassi F, Ferdeghini M, Aria G
Istituto di Clinica Chirurgica Veterinaria, Università di Pisa, Italy.
J Reprod Fertil Suppl. 1993;47:425-31.
Records of elective abortion in 27 bitches presented to the Veterinary Surgery and Reproduction Clinic of the University of Pisa were reviewed. Treatment consisted of twice-daily subcutaneous injections of 150-270 micrograms natural prostaglandin F2 alpha kg-1 for 4 consecutive days starting between cytological dioestrous days 5 and 19. None of the treated bitches whelped. Luteolysis appeared to be complete (serum progesterone < 3.2 nmol l-1) at the end of treatment in 22 of 25 bitches in which progesterone was assayed in serum obtained daily during therapy. Serum progesterone rose after treatment to a concentration consistent with pregnancy in four of 17 bitches in which progesterone was measured once between dioestrous days 23 and 51. The mean intercycle interval (pro-oestrus-pro-oestrus) of the cycle in which abortion was induced was 134 +/- 45 days for 15 dogs for which the interval could be determined, and was significantly shorter than the average preceding interoestrous intervals (210 +/- 40.0 days) for the same dogs (P < 0.001).
回顾了提交至比萨大学兽医外科与繁殖诊所的27只母犬的选择性堕胎记录。治疗方法为，从细胞学双相期第5天至第19天开始，连续4天每天皮下注射两次150 - 270微克天然前列腺素F2α/千克。所有接受治疗的母犬均未分娩。在治疗期间每天采集血清检测孕酮的25只母犬中，有22只在治疗结束时黄体溶解似乎完全（血清孕酮<3.2纳摩尔/升）。在双相期第23天至第51天期间对17只母犬检测了一次孕酮，其中4只母犬在治疗后血清孕酮升至与妊娠相符的浓度。对于15只能够确定诱导堕胎周期的母犬，该周期的平均发情间期（发情前期 - 发情前期）为134±45天，显著短于这些母犬之前的平均发情间期（210±40.0天）（P<0.001）。
