Sellal F, Hirsch E, Barth P, Blond S, Marescaux C
Service de Neurologie, Hôpitaux Universitaires de Strasbourg, France.
Mov Disord. 1993 Oct;8(4):515-8. doi: 10.1002/mds.870080418.
A 16-year-old boy presented with a left anterothalamic lesion secondary to an extradural hematoma. A few months later, a right hemidystonia developed. The dystonic posture, which predominated in the right hand, was not associated with any motor deficit or sensory loss. Superficial sensory stimulation of the right palm and forearm and proprioceptive stimuli induced by passive movements of the right thumb decreased the dystonic posture. Electrical stimulation of the left ventroposterolateral nucleus of the thalamus induced a dramatic improvement in the dystonic postures and movement of the upper right limb. This finding suggests that the role of tactile and proprioceptive stimulation should be analyzed in patients presenting with a symptomatic hemidystonia. When such sensory stimulation is effective, thalamic stimulation may be tried in patients whose condition is incapacitating.
一名16岁男孩因硬膜外血肿继发左侧丘脑前病变。几个月后,出现了右侧半身肌张力障碍。以右手为主的肌张力障碍姿势与任何运动缺陷或感觉丧失均无关。对右手掌和前臂进行浅感觉刺激以及通过被动移动右手拇指诱发本体感觉刺激,可减轻肌张力障碍姿势。电刺激左侧丘脑腹后外侧核可使右侧上肢的肌张力障碍姿势和运动得到显著改善。这一发现表明,对于出现症状性半身肌张力障碍的患者,应分析触觉和本体感觉刺激的作用。当这种感觉刺激有效时,对于病情严重影响生活的患者,可尝试进行丘脑刺激。