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深部脑刺激

Deep brain stimulation.

作者信息

Chen X L, Xiong Y Y, Xu G L, Liu X F

机构信息

Department of Neurology, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.

出版信息

Interv Neurol. 2013 Sep;1(3-4):200-12. doi: 10.1159/000353121.

DOI:10.1159/000353121
PMID:25187779
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4031775/
Abstract

Deep brain stimulation (DBS) has provided remarkable therapeutic benefits for people with a variety of neurological disorders. Despite the uncertainty of the precise mechanisms underlying its efficacy, DBS is clinically effective in improving motor function of essential tremor, Parkinson's disease and primary dystonia and in relieving obsessive-compulsive disorder. Recently, this surgical technique has continued to expand to other numerous neurological diseases with encouraging results. This review highlighted the current and potential future clinical applications of DBS.

摘要

深部脑刺激(DBS)已为患有各种神经系统疾病的患者带来了显著的治疗益处。尽管其疗效的确切机制尚不确定,但DBS在临床上可有效改善特发性震颤、帕金森病和原发性肌张力障碍的运动功能,并缓解强迫症。最近,这种外科技术已不断扩展至其他多种神经系统疾病,取得了令人鼓舞的成果。本综述重点介绍了DBS目前及未来可能的临床应用。

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本文引用的文献

1
Pallidal deep brain stimulation in patients with primary generalised or segmental dystonia: 5-year follow-up of a randomised trial.苍白球深部脑刺激治疗原发性全身性或节段性肌张力障碍患者:一项随机试验的 5 年随访结果。
Lancet Neurol. 2012 Dec;11(12):1029-38. doi: 10.1016/S1474-4422(12)70257-0. Epub 2012 Nov 1.
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Deep-brain stimulation for Parkinson's disease.用于帕金森病的深部脑刺激
N Engl J Med. 2012 Oct 18;367(16):1529-38. doi: 10.1056/NEJMct1208070.
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Surgical treatment of Tourette syndrome.手术治疗妥瑞氏综合征。
Neurosci Biobehav Rev. 2013 Jul;37(6):1178-85. doi: 10.1016/j.neubiorev.2012.09.012. Epub 2012 Oct 4.
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Calibration of unified Parkinson's disease rating scale scores to Movement Disorder Society-unified Parkinson's disease rating scale scores.统一帕金森病评定量表评分向运动障碍学会统一帕金森病评定量表评分的校准。
Mov Disord. 2012 Sep 1;27(10):1239-42. doi: 10.1002/mds.25122. Epub 2012 Aug 6.
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Deep brain stimulation surgery for alcohol addiction.脑深部电刺激术治疗酒精成瘾。
World Neurosurg. 2013 Sep-Oct;80(3-4):S28.e21-31. doi: 10.1016/j.wneu.2012.07.011. Epub 2012 Jul 21.
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Randomized trial of deep brain stimulation for Parkinson disease: thirty-six-month outcomes.随机对照试验深部脑刺激治疗帕金森病:36 个月的结果。
Neurology. 2012 Jul 3;79(1):55-65. doi: 10.1212/WNL.0b013e31825dcdc1. Epub 2012 Jun 20.
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Central thalamic deep brain stimulation to promote recovery from chronic posttraumatic minimally conscious state: challenges and opportunities.丘脑中央深部脑刺激促进慢性创伤性最小意识状态的恢复:挑战与机遇。
Neuromodulation. 2012 Jul;15(4):339-49. doi: 10.1111/j.1525-1403.2012.00458.x. Epub 2012 May 24.
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Increased cerebral metabolism after 1 year of deep brain stimulation in Alzheimer disease.阿尔茨海默病患者接受一年深部脑刺激后大脑代谢增加。
Arch Neurol. 2012 Sep;69(9):1141-8. doi: 10.1001/archneurol.2012.590.
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Treatment of motor and non-motor features of Parkinson's disease with deep brain stimulation.脑深部电刺激治疗帕金森病的运动和非运动症状。
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Obesity and brain addiction circuitry: implications for deep brain stimulation.肥胖与大脑成瘾回路:对深部脑刺激的启示。
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