深部脑刺激
Deep brain stimulation.
作者信息
Chen X L, Xiong Y Y, Xu G L, Liu X F
机构信息
Department of Neurology, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
出版信息
Interv Neurol. 2013 Sep;1(3-4):200-12. doi: 10.1159/000353121.
Abstract
Deep brain stimulation (DBS) has provided remarkable therapeutic benefits for people with a variety of neurological disorders. Despite the uncertainty of the precise mechanisms underlying its efficacy, DBS is clinically effective in improving motor function of essential tremor, Parkinson's disease and primary dystonia and in relieving obsessive-compulsive disorder. Recently, this surgical technique has continued to expand to other numerous neurological diseases with encouraging results. This review highlighted the current and potential future clinical applications of DBS.
摘要
深部脑刺激（DBS）已为患有各种神经系统疾病的患者带来了显著的治疗益处。尽管其疗效的确切机制尚不确定，但DBS在临床上可有效改善特发性震颤、帕金森病和原发性肌张力障碍的运动功能，并缓解强迫症。最近，这种外科技术已不断扩展至其他多种神经系统疾病，取得了令人鼓舞的成果。本综述重点介绍了DBS目前及未来可能的临床应用。
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Lancet Neurol. 2012 Dec;11(12):1029-38. doi: 10.1016/S1474-4422(12)70257-0. Epub 2012 Nov 1.
2
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N Engl J Med. 2012 Oct 18;367(16):1529-38. doi: 10.1056/NEJMct1208070.
3
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Neurosci Biobehav Rev. 2013 Jul;37(6):1178-85. doi: 10.1016/j.neubiorev.2012.09.012. Epub 2012 Oct 4.
4
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Mov Disord. 2012 Sep 1;27(10):1239-42. doi: 10.1002/mds.25122. Epub 2012 Aug 6.
5
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6
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7
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9
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10
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