Thorgeirsson A
Acta Derm Venereol. 1978;58(4):323-6.
Cold-curing resin hardeners were examined regarding their sensitization capacity, by the "guinea pig maximization test". All the aliphatic polyamines caused sensitization. Two of the three cycloaliphatic polyamines sensitized all the animals, while one did not sensitize at all. The aromatic amine sensitized one-fifth of the animals studied. The two polyaminoamides sensitized respectively one-fifth and two-thirds of the animals. Two of the four adducts failed to provoke any reactions. The phenolaccelerated adduct of triethylenetetramine sensitized nearly half of the animals. The adduct of isophorondiamine and epoxy resin sensitized three-fourths of the animals. Judging from the above observations, adducts, when void of aliphatic amines, are probably not potential sensitizers. This may perhaps also be true of the polyaminoamides.
通过“豚鼠最大化试验”，对冷固化树脂固化剂的致敏能力进行了研究。所有脂肪族多胺都会引起致敏。三种脂环族多胺中的两种使所有动物致敏，而另一种则完全不会引起致敏。芳香胺使五分之一的受试动物致敏。两种聚氨基酰胺分别使五分之一和三分之二的动物致敏。四种加合物中的两种未引发任何反应。三乙烯四胺的酚加速加合物使近一半的动物致敏。异佛尔酮二胺与环氧树脂的加合物使四分之三的动物致敏。从上述观察结果判断，不含脂肪族胺的加合物可能不是潜在的致敏剂。聚氨基酰胺可能也是如此。
