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幼年母猪终板血管器中神经肽Y和促黄体生成素释放激素免疫反应性结构的免疫细胞化学证明

Immunocytochemical demonstration of neuropeptide Y and luteinizing hormone-releasing hormone-immunoreactive structures in the organum vasculosum laminae terminalis of juvenile gilts.

作者信息

Całka J, Majewski M, Kaleczyc J, Lakomy M

机构信息

Department of Animal Anatomy, Agricultural and Technical University, Olsztyn, Poland.

出版信息

Neurosci Lett. 1993 Aug 6;158(1):21-4. doi: 10.1016/0304-3940(93)90602-h.

DOI:10.1016/0304-3940(93)90602-h
PMID:8233068
Abstract

Immunocytochemical investigations on the immature gilt organum vasculosum laminae terminalis showed extensive neuropeptide Y- and luteinizing hormone-releasing hormone-immunoreactive innervation of the organ. The luteinizing hormone-releasing hormone-containing varicose fibers ran along the organum vasculosum laminae terminalis in close association with blood vessels. The nerve processes originating from well-stained luteinizing hormone-releasing hormone-immunoreactive perikarya were distributed around the organum vasculosum laminae terminalis. The matrix of the organum vasculosum laminae terminalis was abundantly supplied by neuropeptide Y-immunoreactive varicose fibers. Numerous neuropeptide Y-immunoreactive terminals seemed to penetrate the ependymal lining of the organ. From these observations, it is concluded that there are favorable morphological conditions for secretion of neuropeptide Y into the cerebrospinal fluid of the third ventricle and release of luteinizing hormone-releasing hormone into fenestrated capillaries of the organ.

摘要

对未成熟小母猪终板血管器的免疫细胞化学研究显示,该器官有广泛的神经肽Y和促黄体生成素释放激素免疫反应性神经支配。含促黄体生成素释放激素的曲张纤维沿终板血管器走行,与血管紧密相连。源自染色良好的促黄体生成素释放激素免疫反应性神经元胞体的神经突起分布在终板血管器周围。终板血管器的基质由神经肽Y免疫反应性曲张纤维大量供应。许多神经肽Y免疫反应性终末似乎穿透了该器官的室管膜内衬。从这些观察结果得出结论,存在有利于神经肽Y分泌到第三脑室脑脊液中以及促黄体生成素释放激素释放到该器官有窗孔毛细血管中的形态学条件。

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