氨基糖苷类药物的耳蜗耳毒性。
Aminoglycoside cochlear ototoxicity.
作者信息
Matz G J
机构信息
Loyola University Medical Center, Maywood, Illinois.
出版信息
Otolaryngol Clin North Am. 1993 Oct;26(5):705-12.
PMID:8233484
Abstract
The aminoglycoside antibiotics streptomycin, kanamycin, neomycin, gentamicin, tobramycin, amikacin, and netilmicin are discussed in this article on cochlear toxicity of aminoglycosides. Topics discussed include pharmacokinetics, comparative studies on toxicity, toxicity in neonates and children, histopathology, and aminoglycoside monitoring.
摘要
本文在氨基糖苷类药物的耳蜗毒性方面讨论了氨基糖苷类抗生素链霉素、卡那霉素、新霉素、庆大霉素、妥布霉素、阿米卡星和奈替米星。讨论的主题包括药代动力学、毒性比较研究、新生儿和儿童的毒性、组织病理学以及氨基糖苷类药物监测。
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