[Changes of certain biochemical parameters of liver function in patients after allogenic bone marrow transplantation].

The disturbances in bilirubin level, transaminases (GOT, GPT) and alkaline phosphatase (AP) activities in serum of patients undergoing allogeneic bone marrow transplantation are discussed. Hyperbilirubinemia was considered in all, increase in transaminases activity in half of the group of 10 patients after marrow infusion. In the patients displaying hemopoietic reconstitution bilirubin levels returned to normal. In case of bone marrow graft failures or severe complications in posttransplant period the profound abnormalities in tested parameters were encountered, particularly before death. Possible causes of such disturbances in biochemical hepatic parameters are also briefly discussed.