Ohmori H
Department of Physiology, Faculty of Medicine, University of Kyoto, Japan.
Prog Brain Res. 1993;97:7-11. doi: 10.1016/s0079-6123(08)62257-8.
Electrical stimulation of the efferent fiber to the hair cell is known to suppress peripheral auditory function. In isolated hair cells from the chick, acetylcholine (ACh) generated membrane hyperpolarization when a puff was applied at concentrations from 1 microM to 5 mM. Ionophoretic application of ACh generated a membrane hyperpolarization with a rapid time course. This is due to the increase of K conductance and is accompanied by the rise of the [Ca]i.
已知对毛细胞传出纤维进行电刺激会抑制外周听觉功能。在从雏鸡分离出的毛细胞中，当以1微摩尔至5毫摩尔的浓度微量注射乙酰胆碱（ACh）时，会产生膜超极化。离子电泳施加ACh会产生具有快速时间进程的膜超极化。这是由于钾电导增加所致，并伴随着细胞内钙离子浓度（[Ca]i）的升高。
