Ibebunjo C
Department of Clinical Veterinary Medicine, University of Cambridge.
Res Vet Sci. 1993 Sep;55(2):215-23. doi: 10.1016/0034-5288(93)90084-s.
This study investigated the histochemical and morphometric properties of fibres in laryngeal, hyoid, tongue and pharyngeal muscles which contribute in maintaining patency of the upper airway. Muscle specimens from adult female goats were stained for nicotinamide adenine dinucleotide dehydrogenase-tetrazolium reductase and myosin adenosine triphosphatase activities, and the composition and size of the fibre types determined. These muscles contained types 1, 2A, 2B and 2C fibres with type 2 fibres predominating and the fibres possessed oxidative enzyme activity suggesting fast contraction speed and yet moderate resistance to fatigue. Abductor laryngeal muscles contained more type 1 fibres than the adductors. Among pharyngeal muscles fibre size and type 1 fibre composition increased progressively from the hyopharyngeus caudally. Upper airway muscles contained relatively small fibres (range of mean diameter: 25.7 to 46.1 microns) with the pharyngeal and lingualis proprius muscles containing the smallest fibres. These properties might influence the response of upper airway muscles to neuromuscular blocking drugs.
本研究调查了喉、舌骨、舌和咽肌中纤维的组织化学和形态测量特性，这些肌肉有助于维持上呼吸道通畅。对成年雌性山羊的肌肉标本进行烟酰胺腺嘌呤二核苷酸脱氢酶 - 四氮唑还原酶和肌球蛋白腺苷三磷酸酶活性染色，并确定纤维类型的组成和大小。这些肌肉包含1型、2A型、2B型和2C型纤维，其中2型纤维占主导，且这些纤维具有氧化酶活性，表明收缩速度快但抗疲劳能力适中。喉外展肌比内收肌含有更多的1型纤维。在咽肌中，从咽下缩肌向尾端，纤维大小和1型纤维组成逐渐增加。上呼吸道肌肉含有相对较小的纤维（平均直径范围：25.7至46.1微米），其中咽肌和舌固有肌的纤维最小。这些特性可能会影响上呼吸道肌肉对神经肌肉阻滞药物的反应。
