Laraki R, Bletry O, Raguin G, Agbalika F, Bouche P, Léger J M, Perol Y, Godeau P
Service de Médecine Interne, Groupe Hospitalier Pitié-Salpêtrière, Paris.
Rev Neurol (Paris). 1993;149(4):283-8.
Neuromyositis is a very rare type of polymyositis where, beside the usual muscular manifestations, there are signs of peripheral neuropathy which can be found at clinical, electromyographic and/or pathological examination. We have seen between 1983 and 1990 four cases of neuromyositis. The neurological disorder was an axonopathy in two cases which is usual in neuromyositis; in the other two cases, there was a polyradiculoneuritis which seems to be very rare in this syndrome. In the four patients the disease was particularly severe and unresponsive to treatment. One of our patients had HTLV-I infection diagnosed by polymerase chain reaction amplification and in situ hybridization, while the serological test was negative. To our knowledge only three cases of HTLV-I associated neuromyositis have been reported in the literature.
神经肌炎是一种非常罕见的多发性肌炎类型，除了常见的肌肉表现外，在临床、肌电图和/或病理检查中还可发现周围神经病变的迹象。1983年至1990年间，我们共诊治了4例神经肌炎患者。其中2例患者的神经障碍为轴索性神经病，这在神经肌炎中较为常见；另外2例患者表现为多发性神经根神经炎，这在该综合征中似乎非常罕见。这4例患者的病情都特别严重，且对治疗无反应。我们的1例患者通过聚合酶链反应扩增和原位杂交诊断出感染了人类T淋巴细胞病毒I型（HTLV-I），而血清学检测为阴性。据我们所知，文献中仅报道过3例HTLV-I相关性神经肌炎病例。
