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[与人类嗜T淋巴细胞病毒I型相关的原发性多发性肌炎]

[Primary polymyositis associated to HTLV-I].

作者信息

Cartier L, Prina L

机构信息

Departamento de Ciencias Neurológicas, Facultad de Medicina, Universidad de Chile, Hospital del Salvador, Santiago de Chile.

出版信息

Rev Med Chil. 1996 Apr;124(4):461-4.

PMID:9110487
Abstract

We report a 68 years old male with a polymyositis associated to HTLV-I. Diagnosis was based on clinical picture, an increased creatin-phosphokinase levels, electromyography and muscle biopsy. The patient had positive HTLV-I antibodies, measured by particle agglutination test, indirect immunofluorescence and polymerase chain reaction in lymphocytes. Skin biopsy showed a mycosis fungoides. Schirmer test and minor salivary gland biopsy showed a dacryosialoadenitis. There was no central nervous system involvement. This patient is the only with positive HTLV-I antibodies, among 18 patients with polymyositis in whom these antibodies were measured.

摘要

我们报告一名68岁男性,患有与人类嗜T淋巴细胞病毒I型(HTLV-I)相关的多发性肌炎。诊断基于临床表现、肌酸磷酸激酶水平升高、肌电图和肌肉活检。通过颗粒凝集试验、间接免疫荧光法和淋巴细胞聚合酶链反应检测,该患者HTLV-I抗体呈阳性。皮肤活检显示蕈样肉芽肿。泪液分泌试验和小唾液腺活检显示泪腺涎腺炎。无中枢神经系统受累。在18例检测了这些抗体的多发性肌炎患者中,该患者是唯一HTLV-I抗体呈阳性的。

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