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[向十二指肠和空肠内注入营养物质后蛋白水解酶的分泌]

[Secretion of proteolytic enzymes following administration of nutrients into the duodenum and jejunum].

作者信息

Berkos O V, Shchedrunov V V

出版信息

Vopr Pitan. 1976 Jan-Feb(1):47-50.

PMID:823708
Abstract

Infusion of nutrient fluids into the small intestine of dogs provoked the appearance of Pavlov's pouch juice displaying different proteolytic activity. The quantity of the juice was smaller with drop than with jet infusion. The total secretion of enzymes was more abundant in case of drip intraduodenal infusions of a milk and cream mixture, milk, aminocrovine as compared with its average level following introduction of 10 and 20 per cent solutions of sugar, lipomaize, emulsions prepared of dry dairy products and vegetable oil. The infusions into the duodenum and jejunum was followed by secretion of substantial amounts of the pancreatic juice displaying high activity of trypsin, close to that appearing in response to feeding on meat. The concentration of proteases in the intestinal chyme proved then sufficiently high.

摘要

向狗的小肠内输注营养液会引发显示出不同蛋白水解活性的巴甫洛夫小胃汁的出现。滴注时的胃液量比喷射输注时少。与输注10%和20%的糖溶液、脂化剂、由干乳制品和植物油制备的乳液后其平均水平相比,十二指肠内滴注牛奶和奶油混合物、牛奶、氨基酪蛋白时,酶的总分泌量更丰富。向十二指肠和空肠内输注后,会分泌大量显示出高胰蛋白酶活性的胰液,这一活性接近喂食肉类后出现的活性。当时证明肠内容物中蛋白酶的浓度足够高。

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