Choi S, Enzmann D R
Department of Radiology, Stanford University Medical Center, CA 94305-5105.
AJNR Am J Neuroradiol. 1993 Sep-Oct;14(5):1164-6.
This case report of the infantile form of Krabbe disease in a 2 1/2-month-old boy illustrates the complementary findings that may be seen on CT and MR scans. The key finding on the CT scan was increased density in a bilateral symmetrical distribution involving the thalami with extension into the centrum semiovale. The MR scan, on the other hand, more clearly showed demyelination in the brain stem and cerebellum. In cases in which this involvement is minimal or absent, the MR scan may fail to detect an abnormality, and a CT scan will, therefore, still be necessary to detect characteristic abnormalities.
本病例报告了一名2个半月大男婴的婴儿型克拉伯病，展示了CT和MR扫描可能发现的补充性结果。CT扫描的关键发现是双侧对称分布的密度增加，累及丘脑并延伸至半卵圆中心。另一方面，MR扫描更清晰地显示了脑干和小脑的脱髓鞘。在受累程度轻微或无受累的情况下，MR扫描可能无法检测到异常，因此仍需要CT扫描来检测特征性异常。
