Jespersen A
Acta Pathol Microbiol Scand B. 1976 Oct;84B(5):273-79. doi: 10.1111/j.1699-0463.1976.tb01937.x.
Groups of red mice and CF1 mice immunized intravenously with varying doses of a weak and a strong strain of BCG and a strain of M. tuberculosis were challenged 3-4 weeks later with 2 or 0.5 mg of purified tuberculin injected intravenously. The shock sensitivity of the animals in the individual groups was evaluated on the basis of the number of deaths and the survival times after challenge. In the red mice, the strain of M. tuberculosis induced a significantly greater sensitivity than the BCG strains. The strong strain of BCG induced a slightly greater sensitivity than the weak strain, but the difference was not significant. The CF1 mice were more sensitive to tuberculin shock than the red mice, but any difference in the sensitivity of the animals in the individual groups immunized with the three strains could not be demonstrated.
将不同剂量的弱毒和强毒卡介苗菌株以及一株结核分枝杆菌静脉注射免疫的红小鼠和CF1小鼠组，在3 - 4周后静脉注射2毫克或0.5毫克纯化结核菌素进行攻击。根据攻击后各组动物的死亡数量和存活时间评估动物的休克敏感性。在红小鼠中，结核分枝杆菌菌株诱导的敏感性明显高于卡介苗菌株。强毒卡介苗菌株诱导的敏感性略高于弱毒菌株，但差异不显著。CF1小鼠对结核菌素休克比红小鼠更敏感，但在用三种菌株免疫的各组动物的敏感性上未显示出任何差异。
