Coyle P K, Krupp L B, Doscher C
Department of Neurology, School of Medicine, SUNY.
Ann Neurol. 1993 Nov;34(5):745-7. doi: 10.1002/ana.410340521.
Nineteen of 283 consecutive patients evaluated in the Multiple Sclerosis (MS) Comprehensive Care Center had a borderline or positive B. burgdorferi serology. In 8 patients a repeat serology was nonconfirmatory. Cerebrospinal fluid was examined in 10 seropositive patients and showed anti-B. burgdorferi antibodies without intrathecal production in 5 patients. Antibiotic treatment did not prevent subsequent neurological relapses. The finding of reactive Lyme serology in an MS patient with no suggestive features of the infection is unlikely to indicate neurological Lyme disease.
在多发性硬化症（MS）综合护理中心接受评估的283例连续患者中，有19例患者的伯氏疏螺旋体血清学检测结果处于临界值或呈阳性。8例患者的重复血清学检测结果未得到确认。对10例血清学阳性患者的脑脊液进行了检查，其中5例患者的脑脊液显示有抗伯氏疏螺旋体抗体，但无鞘内产生。抗生素治疗未能预防随后的神经功能复发。在没有感染提示特征的MS患者中发现反应性莱姆血清学结果不太可能表明患有神经莱姆病。
