Chmielewska-Badora J, Cisak E, Dutkiewicz J
Department of Occupational Biohazards, Institute of Agricultural Medicine, Jaczewskiego 2, 20-090 Lublin, Poland.
Ann Agric Environ Med. 2000;7(2):141-3.
A total of 769 adult neurological patients hospitalised in clinics and hospitals situated in the Lublin region (eastern Poland) were examined during the years 1997-2000 with ELISA test for the presence of anti-Borrelia burgdorferi sensu lato antibodies. A statististically significant (p=0.0422) relationship was found between the clinically confirmed diagnosis of multiple sclerosis and the positive serologic reaction with Borrelia antigen. Ten out 26 patients with multiple sclerosis (38.5%) showed positive serologic reaction to Borrelia, whereas among the total number of examined neurological patients the frequency of positive findings was twice as low (19.4%). The result suggests that multiple sclerosis may be often associated with Borrelia infection
1997年至2000年期间，对波兰东部卢布林地区诊所和医院收治的769例成年神经科患者进行了检测，采用酶联免疫吸附测定（ELISA）试验检测抗伯氏疏螺旋体广义抗体的存在。在临床确诊的多发性硬化症与针对伯氏疏螺旋体抗原的阳性血清学反应之间发现了具有统计学意义（p=0.0422）的关系。26例多发性硬化症患者中有10例（38.5%）对伯氏疏螺旋体呈阳性血清学反应，而在接受检查的神经科患者总数中，阳性结果的发生率低两倍（19.4%）。该结果表明，多发性硬化症可能常与伯氏疏螺旋体感染有关。
