Behrns K E, Smith C D, Kelly K A, Sarr M G
Department of Surgery, Mayo Clinic, Rochester, Minnesota.
Ann Surg. 1993 Nov;218(5):646-53. doi: 10.1097/00000658-199321850-00010.
The purpose of this study was to determine the spectrum of presentation, safety, and efficacy of operative bariatric surgery.
The only lasting therapy for medically complicated clinically severe obesity is bariatric surgery. Several operative approaches have resulted in disappointing long-term weight loss or an unacceptable incidence of complications that require revisionary surgery.
Sixty-one consecutive patients who underwent reoperative bariatric surgery from 1985 to 1990 were observed prospectively. One, two, or three previous bariatric procedures had been performed in 77%, 18%, and 5% of patients, respectively. Reoperation was required for unsatisfactory weight loss after gastroplasty or gastric bypass (61%), metabolic complications of jejunoileal bypass (23%), or other complications (16%), including stomal obstruction, alkaline- or acid-reflux esophagitis, and anastomotic ulcer. Revisionary procedures included conversion to vertical banded gastroplasty (33% of operations) and vertical Roux-en-Y gastric bypass (52% of operations); partial pancreato-biliary bypass was used selectively in four patients with severe, medically complicated obesity.
A single patient died postoperatively of a pulmonary embolus; serious morbidity occurred in 11%. Weight loss (mean +/- SEM) after reoperation for unsuccessful weight loss was greater with gastric bypass than with vertical banded gastroplasty (54 +/- 6% versus 24 +/- 6% of excess body weight). Metabolic complications of jejunoileal bypass were corrected, but 67% of the patients were dissatisfied with their postoperative lifestyle because of changes in eating habits or weight gain (64% of patients). Stomal complications and esophageal reflux symptoms were reversed in all patients.
Reoperative bariatric surgery in selected patients is safe and effective for unsatisfactory weight loss or for complications of previous bariatric procedures. Conversion to gastric bypass provides more effective weight loss than vertical banded gastroplasty.
本研究旨在确定减肥手术的临床表现范围、安全性及疗效。
对于患有复杂内科疾病的临床重度肥胖患者,唯一持久的治疗方法是减肥手术。几种手术方式导致长期体重减轻效果令人失望,或出现需要再次手术的不可接受的并发症发生率。
对1985年至1990年间连续接受再次减肥手术的61例患者进行前瞻性观察。分别有77%、18%和5%的患者曾接受过一次、两次或三次先前的减肥手术。再次手术的原因包括胃成形术或胃旁路术后体重减轻不理想(61%)、空肠回肠旁路术的代谢并发症(23%)或其他并发症(16%),包括吻合口梗阻、碱性或酸性反流性食管炎及吻合口溃疡。再次手术方式包括转为垂直束带胃成形术(占手术的33%)和垂直Roux-en-Y胃旁路术(占手术的52%);对于4例患有严重内科复杂疾病的肥胖患者,选择性地采用了部分胰胆分流术。
1例患者术后死于肺栓塞;严重并发症发生率为11%。因体重减轻未成功而再次手术,胃旁路术后体重减轻(平均±标准误)比垂直束带胃成形术更显著(分别为超重体重的54±6%和24±6%)。空肠回肠旁路术的代谢并发症得到纠正,但67%的患者因饮食习惯改变或体重增加(64%的患者)对术后生活方式不满意。所有患者的吻合口并发症及食管反流症状均得到缓解。
对特定患者进行再次减肥手术,对于体重减轻不理想或先前减肥手术的并发症而言是安全有效的。转为胃旁路术比垂直束带胃成形术能更有效地减轻体重。