Drenick E J, Bale G S, Seltzer F, Johnson D G
JAMA. 1980 Feb 1;243(5):443-5.
A group of 200 morbidly obese men (average weight, 143.5 kg; age, 23 to 70 years) were admitted to a weight control program between 1960 and 1977 and were followed up for a mean period of 7 1/2 years. There was complete follow-up until the termination of the study or until death for 185 men. Fifteen men were followed up for fractional periods. Fifty of the 200 died during the course of the study. Life-table techniques, comparing the mortality among the obese with that among men in the general population, demonstrated a 12-fold excess mortality in the obese in the age group 25 to 34 years and a sixfold excess in the age group 35 to 44 years. This ratio diminished with advancing age. Cardiovascular disease was reported as the cause of death more frequently and malignancies less frequently than they were for men in the US general population.
1960年至1977年间，一组200名病态肥胖男性（平均体重143.5千克；年龄23至70岁）参加了一个体重控制项目，并接受了平均7.5年的随访。185名男性接受了完整随访，直至研究结束或死亡。15名男性接受了部分时间段的随访。200名男性中有50名在研究过程中死亡。采用生命表技术，将肥胖者的死亡率与一般人群男性的死亡率进行比较，结果显示，25至34岁年龄组的肥胖者死亡率高出12倍，35至44岁年龄组高出6倍。随着年龄增长，这一比例逐渐降低。与美国一般人群男性相比，心血管疾病被报告为死亡原因的频率更高，而恶性肿瘤的频率更低。
