5-羟甲基嘧啶的合成及生物学特性
Synthesis and biological properties of 5-hydroxy-methylpyrimidines.
作者信息
Cieplik J, Machoń Z, Zimecki M, Wieczorek Z
机构信息
Organic Chemistry Department, Medical Academy, Wrocław, Poland.
出版信息
Arch Immunol Ther Exp (Warsz). 1993;41(1):11-5.
PMID:8239903
Abstract
Reduction of 4-arylamine-6-methyl-2-phenyl-5-pyrimidine carboxylic acid and its ethyl esters as well as 5,7-dihydrofuro (3,4-d)-pyrimidines resulted in obtaining some 4-arylamine-6-methyl-2-phenyl-5-hydroxymethylpyrimidines exhibiting strong immunomodulatory and cytostatic properties.
摘要
4-芳基氨基-6-甲基-2-苯基-5-嘧啶羧酸及其乙酯以及5,7-二氢呋喃并(3,4-d)-嘧啶的还原反应，得到了一些具有强免疫调节和细胞抑制特性的4-芳基氨基-6-甲基-2-苯基-5-羟甲基嘧啶。
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