• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

细胞因子作为器官移植排斥和耐受的介质。

Cytokines as mediators of organ graft rejection and tolerance.

作者信息

Dallman M J

机构信息

University of Oxford, Nuffield Department of Surgery, John Radcliffe Hospital, Headington, UK.

出版信息

Curr Opin Immunol. 1993 Oct;5(5):788-93. doi: 10.1016/0952-7915(93)90138-i.

DOI:10.1016/0952-7915(93)90138-i
PMID:8240741
Abstract

The analysis of cytokines following organ transplantation continues to flourish as a major area of investigation for transplant biologists. Over the past year many papers have reported the use of both molecular and antibody-based tools to dissect the expression of cytokines during graft rejection in both experimental and clinical transplantation. Further, how the expression of cytokines is altered during the induction of tolerance has been investigated by several groups.

摘要

器官移植后细胞因子的分析作为移植生物学家的一个主要研究领域,仍在蓬勃发展。在过去的一年里,许多论文报道了使用分子工具和基于抗体的工具来剖析实验性和临床移植中移植物排斥反应期间细胞因子的表达。此外,几个研究小组还研究了在诱导免疫耐受过程中细胞因子的表达是如何改变的。

相似文献

1
Cytokines as mediators of organ graft rejection and tolerance.细胞因子作为器官移植排斥和耐受的介质。
Curr Opin Immunol. 1993 Oct;5(5):788-93. doi: 10.1016/0952-7915(93)90138-i.
2
Cytokines are involved in the rejection of small intestine allografts.细胞因子参与小肠同种异体移植物的排斥反应。
Transplant Proc. 1997 May;29(3):1802. doi: 10.1016/s0041-1345(97)82000-3.
3
Distinct intragraft cytokine gene expression patterns during acute hepatic rejection under cyclosporine versus FK 506 primary immunosuppression.环孢素与FK506初始免疫抑制下急性肝排斥反应期间移植物内细胞因子基因表达模式的差异
Transplant Proc. 1994 Dec;26(6):3111-3.
4
Intragraft cytokine and cytotoxic T lymphocyte (CTL) specific protein expression as predictors of rat small intestine transplant rejection.移植物内细胞因子和细胞毒性T淋巴细胞(CTL)特异性蛋白表达作为大鼠小肠移植排斥反应的预测指标。
Transplant Proc. 1994 Jun;26(3):1520-1.
5
Common and sequential overexpression patterns of T-helper cytokines during acute (cellular) rejection, and correlation of proinflammatory cytokine expression with chronic (ductopenic) rejection of human liver allografts: a study under cyclosporine, FK 506, and quadruple BT 563 immunosuppression.人肝移植急性(细胞性)排斥反应期间T辅助细胞因子常见和连续的过表达模式,以及促炎细胞因子表达与慢性(胆管减少性)排斥反应的相关性:一项在环孢素、FK 506和四联BT 563免疫抑制下的研究
Transplant Proc. 1995 Feb;27(1):1152-4.
6
T10B9 action: the effect of anti-T-cell antibody mitogenicity and graft rejection on the first dose cytokine response.T10B9作用:抗T细胞抗体促有丝分裂活性及移植物排斥对首剂细胞因子反应的影响
Transplant Proc. 1997 Feb-Mar;29(1-2):315-6. doi: 10.1016/s0041-1345(96)00281-3.
7
Immune Tolerance and Rejection in Organ Transplantation.器官移植中的免疫耐受与排斥反应
Methods Mol Biol. 2019;1899:159-180. doi: 10.1007/978-1-4939-8938-6_12.
8
Analysis of cytokine mRNA expression in syngeneic islet grafts of NOD mice: interleukin 2 and interferon gamma mRNA expression correlate with graft rejection and interleukin 10 with graft survival.非肥胖型糖尿病(NOD)小鼠同基因胰岛移植中细胞因子mRNA表达分析:白细胞介素2和干扰素γ mRNA表达与移植排斥相关,而白细胞介素10与移植存活相关。
Diabetologia. 1994 Aug;37(8):833-7. doi: 10.1007/BF00404341.
9
Cytokines and transplantation: a clinical perspective.
Transplant Sci. 1994 Dec;4 Suppl 1:S9-19.
10
Experimental and clinical allogeneic heart transplant rejection: correlations between histology and immune reactivity detected by cytokine messenger RNA.实验性和临床同种异体心脏移植排斥反应:细胞因子信使核糖核酸检测到的组织学与免疫反应性之间的相关性
J Heart Lung Transplant. 1996 Aug;15(8):778-89.

引用本文的文献

1
Characterization of immune phenotypes in peripheral blood of adult renal transplant recipients using mass cytometry (CyTOF).使用质谱流式细胞术(CyTOF)对成年肾移植受者外周血中的免疫表型进行表征。
Immunohorizons. 2025 Feb 18;9(4). doi: 10.1093/immhor/vlae013.
2
The Polymorphism -308G/A of Gene Modulates the Effect of Immunosuppressive Treatment in First Kidney Transplant Subjects Who Suffer an Acute Rejection.基因的-308G/A多态性调节首次肾移植后发生急性排斥反应患者免疫抑制治疗的效果。
J Immunol Res. 2016;2016:2197595. doi: 10.1155/2016/2197595. Epub 2016 Sep 29.
3
Cytokine gene polymorphisms in acute cellular rejection following living donor liver transplantation: analysis of 155 donor-recipient pairs.
活体供肝移植后急性细胞排斥反应中的细胞因子基因多态性:155对供受者配对分析
Hepatol Int. 2013 Jul;7(3):916-22. doi: 10.1007/s12072-013-9443-2. Epub 2013 Jul 31.
4
Aberrant production of Th1/Th2/Th17-related cytokines in serum of C57BL/6 mice after short-term formaldehyde exposure.短期甲醛暴露后C57BL/6小鼠血清中Th1/Th2/Th17相关细胞因子的异常产生。
Int J Environ Res Public Health. 2014 Sep 26;11(10):10036-50. doi: 10.3390/ijerph111010036.
5
Ischaemic/reperfusion injury: Role of infliximab.缺血/再灌注损伤:英夫利昔单抗的作用
World J Transplant. 2012 Jun 24;2(3):35-40. doi: 10.5500/wjt.v2.i3.35.
6
Interleukin-10-1082G/A polymorphism and acute liver graft rejection: a meta-analysis.白细胞介素-10-1082G/A 多态性与急性肝移植排斥反应:荟萃分析。
World J Gastroenterol. 2012 Feb 28;18(8):847-54. doi: 10.3748/wjg.v18.i8.847.
7
Differential role for competitive reverse transcriptase-polymerase chain reaction and intracellular cytokine staining as diagnostic tools for the assessment of intragraft cytokine profiles in rejecting and nonrejecting heart allografts.竞争性逆转录聚合酶链反应和细胞内细胞因子染色作为诊断工具在评估排斥和非排斥心脏同种异体移植物中移植物内细胞因子谱方面的差异作用。
Am J Pathol. 2000 Nov;157(5):1453-8. doi: 10.1016/S0002-9440(10)64783-9.
8
Analysis of cytokine dynamics in corneal allograft rejection.角膜移植排斥反应中细胞因子动力学分析
Proc Biol Sci. 1999 Nov 7;266(1434):2217-23. doi: 10.1098/rspb.1999.0911.
9
T lymphocyte adhesion mechanisms within inflamed human kidney: studies with a Stamper-Woodruff assay.炎症状态下人肾内的T淋巴细胞黏附机制:采用斯坦珀-伍德拉夫试验的研究
Am J Pathol. 1999 Feb;154(2):503-14. doi: 10.1016/S0002-9440(10)65296-0.
10
Sequential cytokine dynamics in chronic rejection of rat renal allografts: roles for cytokines RANTES and MCP-1.大鼠肾移植慢性排斥反应中细胞因子的动态变化:趋化因子RANTES和MCP-1的作用
Proc Natl Acad Sci U S A. 1995 Sep 12;92(19):8729-33. doi: 10.1073/pnas.92.19.8729.