Kim H J, Park C H, Kang C M, Park H C, Kim C Y, Cho Y S
Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
J Korean Med Sci. 1993 Jun;8(3):230-4. doi: 10.3346/jkms.1993.8.3.230.
The thromboembolic complications of nephrotic syndrome are reasonably common, including spontaneous peripheral venous and/or arterial, pulmonary arterial, and renal venous occlusions. However, in comparison to the relatively high incidence of the venous thromboembolic complications with hypercoagulable status, arterial thromboses have been reported much less and it was only 20 cases in the English literature so far. Furthermore, the most cases were pediatric patients rather than adults. Therefore, this report describes an adult nephrotic cases complicated by superior mesenteric artery thrombosis leading to death via catastrophic hospital course. Also, we reviewed the literature in English regarding cases of arterial thromboses in adult nephrotic patients with special interest to locations of thrombosis, underlying histopathologic types of glomerulopathy, and use of steroids or diuretics before its development.
肾病综合征的血栓栓塞并发症相当常见，包括自发性外周静脉和/或动脉、肺动脉及肾静脉闭塞。然而，与高凝状态下静脉血栓栓塞并发症的相对高发病率相比，动脉血栓形成的报道要少得多，迄今为止英文文献中仅有20例。此外，大多数病例为儿科患者而非成人。因此，本报告描述了一例成人肾病患者并发肠系膜上动脉血栓形成，最终因灾难性的病程导致死亡。同时，我们检索了英文文献中有关成人肾病患者动脉血栓形成的病例，特别关注血栓形成的部位、潜在的肾小球病组织病理学类型以及血栓形成前使用类固醇或利尿剂的情况。
