Nobbs M C, Chan-Lam D, Howell R T, Kitchen C, Copplestone J A
South Western Regional Cytogenetics Centre, Southmead Hospital, Bristol, U.K.
Cancer Genet Cytogenet. 1993 Oct 15;70(2):144-5. doi: 10.1016/0165-4608(93)90187-q.
A patient with ANLL FAB subtype M1 was found to possess a t(16;21)(p11;q22) and trisomy 10. The 16;21 translocation has been reported in 12 other cases of ANLL, of various subtypes, and its relationship to the disease profile is discussed.