Translocation t(1;10) (q21;q26) in a case of acute nonlymphocytic leukemia.

作者信息

Terreros M C, Quesada M, Slavutsky I R

机构信息

Servicio de Anatomia Patológica, Hospital Neuropsiquiátrico Especializado Dr. Alejandro Korn, Melchor Romero, La Plata, Argentina.

出版信息

Acta Haematol. 1998;99(2):92-4. doi: 10.1159/000040818.

DOI:10.1159/000040818

PMID:9554457

Abstract

Chromosome banding studies carried out on bone marrow cells from a 16 year-old boy with an M1 acute nonlymphocytic leukemia (ANLL) revealed an unbalanced translocation involving chromosomes 1 and 10: der(10) t(1;10) (q21;q26) that results in a partial trisomy 1q between bands 1q21-1qter. Marker del(6)(q21) and trisomies of chromosomes 18, 21 and 22 were also observed. To our knowledge, this der(10) is the first to be reported in a patient with ANLL.

摘要