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子宫内膜腺癌的核仁组织区相关蛋白与雌激素受体

[Nucleolar organizer region-associated proteins and estrogen receptor of endometrial adenocarcinoma].

作者信息

Wan Z M

机构信息

International peace Hospital, Shijiazhuang.

出版信息

Zhonghua Fu Chan Ke Za Zhi. 1993 May;28(5):287-8, 315.

PMID:8243149
Abstract

The nucleolar organizer region-associated proteins (AgNOR) staining technique and estrogen receptor (ER) detective technique were applied to endometrial adenocarcinoma in grade 1-4 and endometrial cystic hyperplasia. The results showed that there was no significant difference of AgNOR numbers between the grade I endometrial adenocarcinoma and endometrial cystic hyperplasia, while a significant difference of the number, size and localization of the nuclei was observed between endometrial adenocarcinoma and grade 2-4 endometrial adenocarcinoma (P < 0.001). The ER content in well differentiated endometrial adenocarcinoma was more than poor differentiated ones.

摘要

将核仁组成区相关蛋白(AgNOR)染色技术和雌激素受体(ER)检测技术应用于1 - 4级子宫内膜腺癌及子宫内膜囊性增生。结果显示,Ⅰ级子宫内膜腺癌与子宫内膜囊性增生之间AgNOR数量无显著差异,而子宫内膜腺癌与2 - 4级子宫内膜腺癌之间在细胞核数量、大小及定位方面观察到显著差异(P < 0.001)。高分化子宫内膜腺癌中的ER含量多于低分化者。

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