Sheffield P A, Moore D E, Voigt L F, Scholes D, Wang S P, Grayston J T, Daling J R
University of Washington, Seattle.
Fertil Steril. 1993 Dec;60(6):970-5. doi: 10.1016/s0015-0282(16)56394-8.
To determine whether pelvic damage is associated with positive Chlamydia trachomatis serology in women with tubal ectopic pregnancy.
Cross-sectional retrospective study.
A prepaid health maintenance organization.
Two-hundred eighty-one women admitted with confirmed tubal ectopic pregnancy were interviewed for history of sexually transmitted diseases. Chlamydia serology was obtained for 135 subjects, and operative findings were available for 121 of these.
None.
Pelvic damage, as determined by review of operative findings of the pelvis at the time of ectopic surgery.
Pelvic damage was associated with positive chlamydia serology with an adjusted odds ratio of 4.2 (95% confidence interval: 1.8 to 9.7). Moderate and severe pelvic damage were more strongly associated with positive serology than mild damage.
Women with ectopic pregnancies and antibodies to C. trachomatis are more likely to have damaged pelves than women with ectopic pregnancies without such antibodies. Prevention or early treatment of C. trachomatis infection may reduce pelvic damage and, therefore, reduce incidence of ectopic pregnancy.
确定输卵管异位妊娠女性的盆腔损伤是否与沙眼衣原体血清学阳性有关。
横断面回顾性研究。
一家预付式健康维护组织。
对281名确诊为输卵管异位妊娠的女性进行了性传播疾病病史访谈。135名受试者进行了衣原体血清学检测，其中121名受试者有手术结果。
无。
通过回顾异位手术时盆腔的手术结果来确定盆腔损伤。
盆腔损伤与衣原体血清学阳性相关，校正比值比为4.2（95%置信区间：1.8至9.7）。与轻度损伤相比，中度和重度盆腔损伤与血清学阳性的相关性更强。
与没有此类抗体的异位妊娠女性相比，有异位妊娠且沙眼衣原体抗体阳性的女性更有可能出现盆腔损伤。预防或早期治疗沙眼衣原体感染可能会减少盆腔损伤，从而降低异位妊娠的发生率。
