Jakubiczka S, Schnieders F, Schmidtke J
Institut für Humangenetik, Medizinische Hochschule Hannover, Germany.
Genomics. 1993 Sep;17(3):732-5. doi: 10.1006/geno.1993.1394.
We have isolated a male-specific bovine genomic homologue of the human TSPY gene (testis-specific protein, Y-encoded). Two specific transcripts can be detected in bovine testicular RNA. The cloned sequence represents one copy of a clustered array of some 50-200 related sequences on the Y chromosome resembling the arrangement present in the human genome. The clone isolated from the bovine genome has two regions that are highly conserved between homo and bos. One stretch of DNA is homologous in 45 of 51 bp (88%), and the other stretch shares 71 of 100 bp (71%).
我们已经分离出人类TSPY基因（Y染色体编码的睾丸特异性蛋白）的一个雄性特异性牛基因组同源物。在牛睾丸RNA中可检测到两种特异性转录本。克隆的序列代表Y染色体上约50 - 200个相关序列的簇状阵列中的一个拷贝，类似于人类基因组中的排列。从牛基因组中分离出的克隆有两个在人和牛之间高度保守的区域。一段DNA在51个碱基对中有45个是同源的（88%），另一段在100个碱基对中有71个是同源的（71%）。
