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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Hendry B M, Urban B W, Haydon D A

Biochim Biophys Acta. 1978 Oct 19;513(1):106-16. doi: 10.1016/0005-2736(78)90116-5.

In monooelein bilayers made highly conducting by the addition of a fixed amount of o-pyromellitylgramicidin, the membrane conductance has been shown to be strongly dependent on the chain length of the n-alkane with which the membrane is in equilibrium. Thus for n-hexadecane, the conductance is larger by approx. 10(4) times than it is for n-octane. This result is independent of whether the polypeptide is introduced via the aqueous or lipid phases. 2. The observed conductance variations have been accounted for in terms of a mechanism (outlined in earlier publications) which is based on the thickness and tension changes produced in bilayers by the adsorption of n-alkanes. Essentially quantitative agreement between theory and experiment is found.

在通过添加固定量的邻苯二甲酰亚胺短杆菌肽而具有高导电性的单油酸甘油酯双层膜中，已表明膜电导强烈依赖于与膜处于平衡状态的正构烷烃的链长。因此，对于正十六烷，电导率比正辛烷大约大10⁴倍。该结果与多肽是通过水相还是脂质相引入无关。2. 观察到的电导变化已根据一种机制（在早期出版物中概述）进行了解释，该机制基于正构烷烃吸附在双层膜中产生的厚度和张力变化。理论与实验之间发现了基本的定量一致性。

Hendry B M, Urban B W, Haydon D A

Biochim Biophys Acta. 1978 Oct 19;513(1):106-16. doi: 10.1016/0005-2736(78)90116-5.

In monooelein bilayers made highly conducting by the addition of a fixed amount of o-pyromellitylgramicidin, the membrane conductance has been shown to be strongly dependent on the chain length of the n-alkane with which the membrane is in equilibrium. Thus for n-hexadecane, the conductance is larger by approx. 10(4) times than it is for n-octane. This result is independent of whether the polypeptide is introduced via the aqueous or lipid phases. 2. The observed conductance variations have been accounted for in terms of a mechanism (outlined in earlier publications) which is based on the thickness and tension changes produced in bilayers by the adsorption of n-alkanes. Essentially quantitative agreement between theory and experiment is found.

在通过添加固定量的邻苯二甲酰亚胺短杆菌肽而具有高导电性的单油酸甘油酯双层膜中，已表明膜电导强烈依赖于与膜处于平衡状态的正构烷烃的链长。因此，对于正十六烷，电导率比正辛烷大约大10⁴倍。该结果与多肽是通过水相还是脂质相引入无关。2. 观察到的电导变化已根据一种机制（在早期出版物中概述）进行了解释，该机制基于正构烷烃吸附在双层膜中产生的厚度和张力变化。理论与实验之间发现了基本的定量一致性。