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Probes for the study of mupirocin resistance in staphylococci.

作者信息

Rahman M, Noble W C, Dyke K G

机构信息

Department of Microbial Diseases, St John's Institute of Dermatology, St Thomas' Hospital, London.

出版信息

J Med Microbiol. 1993 Dec;39(6):446-9. doi: 10.1099/00222615-39-6-446.

DOI:10.1099/00222615-39-6-446
PMID:8246263
Abstract

Probes constructed from a 4.05-kb EcoRI digest fragment of a mupirocin resistance plasmid and a 751-bp internal part of this fragment hybridised with DNA from all of 36 independent high-level mupirocin-resistant staphylococci tested from seven centres; most were Staphylococcus aureus. In most instances the probes detected an EcoRI digest fragment of approximately 4 kb. Probes did not hybridise to DNA from low-level resistant strains, nor from strains sensitive to mupirocin.

摘要

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