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高水平莫匹罗星耐药性从溶血葡萄球菌向其他葡萄球菌的接合转移。

Conjugative transfer of high-level mupirocin resistance from Staphylococcus haemolyticus to other staphylococci.

作者信息

Udo E E, Jacob L E, Mokadas E M

机构信息

Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait.

出版信息

Antimicrob Agents Chemother. 1997 Mar;41(3):693-5. doi: 10.1128/AAC.41.3.693.

Abstract

A conjugative plasmid, pXU10, encoding high-level mupirocin resistance was transferred from a Staphylococcus haemolyticus isolate, CN216, to other coagulase-negative staphylococci and a restriction deficient Staphylococcus aureus strain, XU21, but not to clinical isolates or a restriction-proficient laboratory strain (strain WBG541) of S. aureus. However, from XU21 it was cotransferred with a 3.5-kb chloramphenicol resistance plasmid to WBG541. The results demonstrated the ability of pXU10 to mobilize nonconjugative plasmids.

摘要

一种编码高水平莫匹罗星抗性的接合质粒pXU10,从溶血葡萄球菌分离株CN216转移至其他凝固酶阴性葡萄球菌及一株限制缺陷型金黄色葡萄球菌菌株XU21,但未转移至金黄色葡萄球菌的临床分离株或限制 proficient 实验室菌株(菌株WBG541)。然而,从XU21它与一个3.5 kb的氯霉素抗性质粒共转移至WBG541。结果证明了pXU10调动非接合质粒的能力。 (注:原文中“restriction-proficient”表述有误,推测可能是“restriction-proficient”,这里按照推测翻译为“限制 proficient”,实际可能需要根据正确原文进一步准确翻译)

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Mupirocin resistance in coagulase-negative staphylococci.
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引用本文的文献

本文引用的文献

1
Mupirocin resistance in coagulase-negative staphylococci.
J Med Microbiol. 1993 Dec;39(6):450-3. doi: 10.1099/00222615-39-6-450.
2
Probes for the study of mupirocin resistance in staphylococci.
J Med Microbiol. 1993 Dec;39(6):446-9. doi: 10.1099/00222615-39-6-446.
4
Mupirocin resistance in methicillin-resistant Staphylococcus aureus from a veterans hospital.
Chemotherapy. 1993 Nov-Dec;39(6):400-4. doi: 10.1159/000238984.
6
An investigation of plasmids from Staphylococcus aureus that mediate resistance to mupirocin and tetracycline.
Microbiology (Reading). 1994 Oct;140 ( Pt 10):2577-83. doi: 10.1099/00221287-140-10-2577.

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