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氯米帕明与安慰剂治疗早泄的一项初步研究。

Clomipramine versus placebo in the treatment of premature ejaculation: a pilot study.

作者信息

Segraves R T, Saran A, Segraves K, Maguire E

机构信息

Department of Psychiatry, MetroHealth Medical Center, Cleveland, Ohio.

出版信息

J Sex Marital Ther. 1993 Fall;19(3):198-200. doi: 10.1080/00926239308404904.

DOI:10.1080/00926239308404904
PMID:8246275
Abstract

This study evaluated clomipramine as a possible treatment for premature ejaculation. Twenty patients with premature ejaculation were randomly allocated to treatment with clomipramine or placebo in a double-blind study. Average estimated time to ejaculation after vaginal penetration increased to 6.1 minutes on 25 mg. of clomipramine and to 8.4 minutes on 50 mg. of clomipramine. These estimated times were significantly different from estimated time to ejaculation while on placebo. These findings suggest that low dose clomipramine may be useful in the treatment of premature ejaculation.

摘要

本研究评估了氯米帕明作为早泄可能治疗方法的效果。在一项双盲研究中,20名早泄患者被随机分配接受氯米帕明或安慰剂治疗。阴道插入后平均射精估计时间在服用25毫克氯米帕明时增加到6.1分钟,在服用50毫克氯米帕明时增加到8.4分钟。这些估计时间与服用安慰剂时的射精估计时间有显著差异。这些发现表明低剂量氯米帕明可能对早泄治疗有用。

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