Ueda M, Suzuki H, Kaneda T
Department of Oral Surgery, Nagoya University School of Medicine, Japan.
Nagoya J Med Sci. 1993 Mar;55(1-4):97-101.
A case of solitary intraosseous neurofibroma of the mandible is reported. The tumor was located in the body of the right mandible. Segmental mandibulectomy including the surrounding tissue was performed and the mandible was reconstructed with the free scapular osteocutaneous flap. From histological examination of the resected mandible, typical findings of a tumor invading the adjacent bone along the mandibular nerve were observed. Immunohistochemical examination of the tumor showed positive staining of the tumor cells for anti-S100 protein antibodies. Numerous nerve-like fibers were also noted by Bodian stain.
报告一例下颌骨孤立性骨内神经纤维瘤。肿瘤位于右下颌骨体部。施行包括周围组织的下颌骨节段性切除术，并用游离肩胛皮瓣对下颌骨进行重建。对切除的下颌骨进行组织学检查，观察到肿瘤沿下颌神经侵犯相邻骨的典型表现。肿瘤的免疫组织化学检查显示肿瘤细胞对抗S100蛋白抗体呈阳性染色。用博迪安染色法也观察到许多神经样纤维。
