Guillaud R, Schved J F, Gris J C, Chapuis H, Marty-Double C, Astruc J, Lesbros D
Services de pédiatrie et néonatalogie, CHRU, Nîmes, France.
Pediatrie. 1993;48(6):459-62.
An 11-year-old girl presented with a typical serologically proven infectious mononucleosis with persistent fever, jaundice and hepatosplenomegaly in spite of steroid therapy. Laboratory tests showed pancytopenia, fibrinopenia and hypertriglyceridemia. The liver biopsy revealed an infiltration with hyperbasophilic cells. One month later, a slight improvement was noted and fever disappeared after 4 days on acyclovir therapy. The authors recall the spectrum of the macrophagic activation syndrome.
一名11岁女孩表现出典型的经血清学证实的传染性单核细胞增多症，尽管接受了类固醇治疗，但仍持续发热、黄疸和肝脾肿大。实验室检查显示全血细胞减少、纤维蛋白原减少和高甘油三酯血症。肝脏活检显示有嗜碱性增强细胞浸润。一个月后，病情稍有改善，在接受阿昔洛韦治疗4天后发热消失。作者回顾了巨噬细胞活化综合征的范围。
