Zahn T P, Kruesi M J
Laboratory of Psychology and Psychopathology, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892.
Psychophysiology. 1993 Nov;30(6):605-14. doi: 10.1111/j.1469-8986.1993.tb02086.x.
Skin conductance (SC) and heart rate (HR) were measured during rest, a series of tones, and a reaction time task in 34 boys with disruptive behavior disorder to ascertain (a) if this broadly defined group differed from control boys (n = 33) and (b) if there were differences within the spectrum related to component diagnoses or to target behaviors. Disruptive boys had higher resting HR than controls, due largely to those without a subdiagnosis of conduct disorder. Disruptive boys showed a smaller increment in SC response frequency for task instructions. They did not show a general deficit in phasic SC reactivity but habituated to signal stimuli at a faster rate than did controls. However, their SC response latencies were shorter despite slower motor reaction time. Responsivity variables were similar in boys with and without a subdiagnosis of conduct disorder. The data are not compatible with the hypothesis of low autonomic nervous system (ANS) baselines in disruptive boys but partially suggest low ANS reactivity. They generally support the validity of the disruptive behavior disorder spectrum. Correlations with measures of aggression and impulsivity suggest that individual differences within the spectrum might be more fruitfully described by behavior dimensions than by conventional subdiagnosis.
对34名患有破坏性行为障碍的男孩在休息、一系列音调刺激以及反应时间任务期间测量了皮肤电导率（SC）和心率（HR），以确定：（a）这个广义定义的群体是否与对照组男孩（n = 33）不同；（b）在该谱系中与组成诊断或目标行为相关的差异是否存在。患有破坏性行为障碍的男孩静息心率高于对照组，这主要归因于那些没有品行障碍亚诊断的男孩。患有破坏性行为障碍的男孩对任务指令的皮肤电导率反应频率增加较小。他们在阶段性皮肤电导率反应性方面没有表现出普遍缺陷，但比对照组更快地适应信号刺激。然而，尽管运动反应时间较慢，他们的皮肤电导率反应潜伏期却较短。有或没有品行障碍亚诊断的男孩的反应性变量相似。这些数据与破坏性行为障碍男孩自主神经系统（ANS）基线较低的假设不相符，但部分表明自主神经系统反应性较低。它们总体上支持破坏性行为障碍谱系的有效性。与攻击性和冲动性测量指标的相关性表明，该谱系内的个体差异可能通过行为维度比通过传统的亚诊断更有效地进行描述。
