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支持血管性青光眼病因的论据。

Arguments for a vascular glaucoma etiology.

作者信息

Sonnsjö B, Krakau C E

机构信息

Department of Experimental Ophthalmology, University Eye Clinic, MAS, Malmö, Sweden.

出版信息

Acta Ophthalmol (Copenh). 1993 Aug;71(4):433-44. doi: 10.1111/j.1755-3768.1993.tb04615.x.

Abstract

A material of Open Angle Glaucoma (G) collected by an eye practitioner (B S) from 1980 to 1991 is analysed with special respect to the occurrence of disc haemorrhages (Hs) and retinal vein occlusions (VOs). There is a close association between Hs and VOs and G, which in all categories increases with increasing follow-up time. Furthermore, the occurrence of mixed cases--H in one eye and VO in the same or the other--support the opinion that Hs, branch vein occlusions and central vein occlusions are manifestations of the same vascular disease, the difference between them being the size of the vessel affected. The well known morphological changes in the retinal veins of glaucomas and in central vein occlusions are endothelial proliferations causing progressive increase of flow resistance. Similar changes most probably also cause branch occlusions and disc haemorrhages. The vascular affection which obstructs the vessels with hindrance of the blood flow and impaired nutrition of neuronal tissue, might be the primary cause of glaucoma.

摘要

一位眼科医生(B S)在1980年至1991年期间收集的开角型青光眼(G)材料,特别针对视盘出血(Hs)和视网膜静脉阻塞(VOs)的发生情况进行了分析。Hs、VOs与G之间存在密切关联,在所有类别中,随着随访时间的增加而增加。此外,混合病例(一只眼为Hs,另一只眼或同一只眼为VO)的出现支持了这样一种观点,即Hs、分支静脉阻塞和中央静脉阻塞是同一血管疾病的表现,它们之间的差异在于受影响血管的大小。青光眼视网膜静脉和中央静脉阻塞中众所周知的形态学变化是内皮细胞增殖,导致血流阻力逐渐增加。类似的变化很可能也会导致分支阻塞和视盘出血。阻碍血管、妨碍血流并损害神经组织营养的血管病变可能是青光眼的主要原因。

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