Yoo Young Cheol, Park Ki Ho
Department of Ophthalmology, Hallym University College of Medicine, Seoul, Korea.
Korean J Ophthalmol. 2007 Dec;21(4):222-7. doi: 10.3341/kjo.2007.21.4.222.
To document the clinical features of disc hemorrhage in patients with branch retinal vein occlusion (BRVO) and normal tension glaucoma (NTG), and to evaluate the relationship between BRVO and NTG with disc hemorrhages.
From July 2001 to May 2006, sixteen patients with both NTG and BRVO in different eyes were successively collected from outpatient population of Seoul National University Hospital in this observational case series. The frequency and location of disc hemorrhages, history of associated systemic diseases, and the order of the time of diagnosis between NTG and BRVO were studied.
All patients had unilateral BRVO, and their mean age was 63.3+/-10.6 years. Disc hemorrhages were detected in eight patients (50%) during the mean follow-up of 26.8 months (range, 3-96 months). Six patients (75%) had disc hemorrhages in the non-BRVO eyes and two patients (25%) in BRVO eyes. Five hemorrhages (62.5%) were located at inferior-temporal quadrant of the optic disc. History of systemic hypertension was identified in 12 patients (75.0%). In 11 patients (68.8%), NTG was diagnosed at the same time as BRVO.
A higher frequency of disc hemorrhages was identified in patients with both BRVO and NTG. Therefore, some cases of NTG, especially with disc hemorrhages, may share a common vascular pathophysiology with BRVO.
记录视网膜分支静脉阻塞（BRVO）合并正常眼压性青光眼（NTG）患者视盘出血的临床特征，并评估BRVO、NTG与视盘出血之间的关系。
在这个观察性病例系列中，于2001年7月至2006年5月期间，从首尔国立大学医院门诊患者中连续收集了16例不同眼患有NTG和BRVO的患者。研究视盘出血的频率和位置、相关全身性疾病史以及NTG和BRVO诊断时间顺序。
所有患者均为单侧BRVO，平均年龄为63.3±10.6岁。在平均26.8个月（范围3 - 96个月）的随访期间，8例患者（50%）检测到视盘出血。6例患者（75%）在非BRVO眼出现视盘出血，2例患者（25%）在BRVO眼出现视盘出血。5处出血（62.5%）位于视盘颞下象限。12例患者（75.0%）有系统性高血压病史。11例患者（68.8%）NTG与BRVO同时诊断。
BRVO合并NTG患者视盘出血的发生率更高。因此，部分NTG病例，尤其是伴有视盘出血的病例，可能与BRVO具有共同的血管病理生理学机制。
