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颗粒状角膜营养不良I型(Groenouw I型)与副蛋白血症性结晶状角膜病变的鉴别诊断

Differential diagnosis between granular corneal dystrophy Groenouw type I and paraproteinemic crystalline keratopathy.

作者信息

Møller H U, Ehlers N, Bojsen-Møller M, Ridgway A E

机构信息

Department of Ophthalmology, Arhus University Hospital, Denmark.

出版信息

Acta Ophthalmol (Copenh). 1993 Aug;71(4):552-5. doi: 10.1111/j.1755-3768.1993.tb04635.x.

DOI:10.1111/j.1755-3768.1993.tb04635.x
PMID:8249591
Abstract

A case of corneal opacities in a leukemic patient with an M-component in the serum proteins is presented, and a comparison is made to patients with granular corneal dystrophy Groenouw type I. The corneal deposits associated with the two conditions may appear identical with slit-lamp biomicroscopy. Granular dystrophy patients, however, show a normal serum immunoglobulin pattern in contrast to patients with paraproteinemic crystalline keratopathy. The two entities can therefore be distinguished from each other by a serum electrophoresis.

摘要

本文报告了一例血清蛋白中有M成分的白血病患者发生角膜混浊的病例,并与I型格罗诺角膜颗粒状营养不良患者进行了比较。在裂隙灯生物显微镜检查下,这两种情况相关的角膜沉积物可能看起来相同。然而,与副蛋白血症结晶性角膜病变患者不同,颗粒状营养不良患者的血清免疫球蛋白模式正常。因此,通过血清电泳可以将这两种疾病区分开来。

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