Sönnichsen N, Barthelmes H
Angew Parasitol. 1976 May;17(2):65-70.
The scabies epidemy being observed since 1965, had developed from persistent endemic centres and pursues continuous the cyclic course of the scabies humanis in periods of 15 to 20 years. The intracutaneous tests with antigens of Notoedres alepis show a cross antigenity with the antigens of Sarcoptes scabiei and a sensibility of patients suffering from scabies. These tests have a diagnostical value. The antigens of Notoedres alepis are free of antigens from human epidermis.--The results support the theory of immunity for the interpretation of the cyclic course of the scabies, whereas wars and social and hygienic nuisances only have a modifying influence, and promiscuity, Sarcoptotoxicity of environment and others have no deciding importance.
自1965年以来观察到的疥疮流行，起源于持续存在的地方性疫源地，并在15至20年的周期内持续呈现人体疥疮的周期性病程。用阿氏诺螨抗原进行的皮内试验显示与疥螨抗原存在交叉抗原性，且疥疮患者有敏感性。这些试验具有诊断价值。阿氏诺螨抗原不含人表皮抗原。——这些结果支持免疫理论对疥疮周期性病程的解释，而战争以及社会和卫生干扰仅具有调节性影响，滥交、环境的疥螨毒性等因素并无决定性意义。
