van Faassen A, Hazen M J, van den Brandt P A, van den Bogaard A E, Hermus R J, Janknegt R A
Department of Urology, State University of Limburg, Maastricht, The Netherlands.
Am J Clin Nutr. 1993 Dec;58(6):917-22. doi: 10.1093/ajcn/58.6.917.
Twenty habitually omnivorous subjects and 19 habitually lactoovovegetarian subjects aged 59-65 y collected feces during 4 consecutive days. The concentrations of bile acids in total feces did not differ between the omnivores and vegetarians, but the bile acid concentrations in fecal water were significantly lower in the vegetarians. The concentration of the colorectal cancer-predicting bile acid deoxycholic acid in fecal water was explained by the intake of saturated fat and the daily fecal wet weight (r2 = 0.50). Fecal pH did not differ between the omnivores and vegetarians. This variable was significantly (P < 0.05) explained by the intake of calcium (r2 = 0.30); 24-h fecal wet weight and defecation frequency were significantly higher in the vegetarians. In conclusion, our vegetarian subjects had a lower concentration of deoxycholic acid in fecal water, higher fecal wet weight, and higher defecation frequency than the omnivorous subjects.
20名年龄在59 - 65岁之间的习惯性杂食者和19名习惯性蛋奶素食者连续4天收集粪便。杂食者和素食者的总粪便中胆汁酸浓度没有差异，但素食者粪便水中的胆汁酸浓度显著较低。粪便水中预测结直肠癌的胆汁酸脱氧胆酸浓度可由饱和脂肪摄入量和每日粪便湿重解释（r2 = 0.50）。杂食者和素食者的粪便pH值没有差异。该变量可由钙摄入量显著（P < 0.05）解释（r2 = 0.30）；素食者的24小时粪便湿重和排便频率显著更高。总之，我们的素食者粪便水中脱氧胆酸浓度低于杂食者，粪便湿重和排便频率高于杂食者。
