Baird I M, Slepack J M, Kauffman C A, Phair J P
Antimicrob Agents Chemother. 1976 Oct;10(4):626-9. doi: 10.1128/AAC.10.4.626.
Pseudomonas aeruginosa resistant to both gentamicin and carbenicillin was isolated with increasing frequency at the Cincinnati Veterans Administration Hospital during the period 1971 to 1974. A comparison of patients from whom P. aeruginosa was isolated during this period failed to reveal any significant clinical differences between the patients colonized or infected with resistant organisms and those colonized or infected with susceptible organisms. Overt clinical infection attributable to either organism was rare. The antibiotic-resistant organisms were isolated most frequently from urine. Isolation of the antibiotic-resistant organisms was more frequent from patients who had previously received gentamicin.
1971年至1974年期间,在辛辛那提退伍军人管理局医院,对庆大霉素和羧苄青霉素均耐药的铜绿假单胞菌分离频率不断增加。对这一时期分离出铜绿假单胞菌的患者进行比较,结果显示,感染耐药菌或被耐药菌定植的患者与感染敏感菌或被敏感菌定植的患者之间,未发现任何显著的临床差异。由这两种细菌引起的明显临床感染都很罕见。耐药菌最常从尿液中分离出来。在之前接受过庆大霉素治疗的患者中,耐药菌的分离更为频繁。