Chadwick P
Can Med Assoc J. 1973 Oct 6;109(7):585-7.
The resistance to gentamicin 4 mug./ml. of 250 Pseudomonas aeruginosa isolates was measured by a proportion method. Twenty-eight (11.2%) of the cultures fell into the most resistant group, in whose populations between 10 and 100% of the organisms were resistant. A relatively high percentage of urinary isolates and a comparatively low percentage of isolates from respiratory sources occurred in this group. Three of the 28 were resistant to carbenicillin 150 mug./ml. and 6 of 18 tested were as resistant to gentamicin 8 mug./ml. as they were to 4 mug./ml. The distribution of Ps. aeruginosa isolates between the different grades of resistance did not change significantly during the 10 months in which the survey was performed.
采用比例法测定了250株铜绿假单胞菌对4微克/毫升庆大霉素的耐药性。28株(11.2%)培养物属于耐药性最强的组,该组中10%至100%的菌株具有耐药性。该组中尿液分离株的比例相对较高,而呼吸道来源的分离株比例相对较低。28株中有3株对150微克/毫升羧苄青霉素耐药,在检测的18株中,有6株对8微克/毫升庆大霉素的耐药性与对4微克/毫升庆大霉素的耐药性相同。在进行调查的10个月期间,不同耐药等级的铜绿假单胞菌分离株分布没有显著变化。