Douglas D M, Ward L, Brown J S
Department of Internal Medicine, Madigan Army Medical Center, Tacoma, Washington.
Ann Allergy. 1993 Nov;71(5):459-60.
Nonsteroidal antiinflammatory drug (NSAID) and aspirin reactions remain commonplace. Specific recommendations and standardized approaches to the use of NSAIDs in patients with known hypersensitivity to these agents are evolving. Cross reactivity and sensitization are frequent within this group of agents. The advent of newer synthetic nonsteroidal antiinflammatory drugs may offer a means of lowering reaction rates. Flurbiprofen (Ansaid) is a new NSAID for the treatment of rheumatoid arthritis and osteoarthritis. We report successful flurbiprofen desensitization with incremental oral challenge in a patient using this agent.
非甾体抗炎药（NSAID）和阿司匹林反应仍然很常见。针对已知对这些药物过敏的患者使用NSAIDs的具体建议和标准化方法正在不断发展。在这类药物中，交叉反应和致敏现象很常见。新型合成非甾体抗炎药的出现可能提供一种降低反应率的方法。氟比洛芬（安赛蜜）是一种用于治疗类风湿性关节炎和骨关节炎的新型NSAID。我们报告了一名使用该药物的患者通过递增口服激发试验成功进行氟比洛芬脱敏的案例。
