Lesbre P, Campeau L, Bourrassa M, Huot R, Quiret J C
Arch Mal Coeur Vaiss. 1976 Sep;69(9):935-42.
On the basis of 150 results on patients who underwent an ECG at submaximal exercise, selective coronary arteriography and cine-arteriography, this study has established that: -- certain elecerographic criteria of coronary insufficiency which have a high predictive value in males (a "near ischeamic" appearance, an J depression at or above 4 mm) are not applicable to the female; -- where an ECG tracing which is abnormal at rest becomes normal on exercise, then in both males and females there is a healthy coronary tree; -- the incidence of false-positives is 22.9%, which is 4 times that found in males; -- propranolol (60 mg orally) returns these pseudo-ischaemic changes in the resting and exercise ECG to normal and affords a simple method of identifying the false positives.
基于对150例进行次极量运动心电图、选择性冠状动脉造影和动脉电影造影的患者的研究结果,本研究确定:——某些在男性中具有高预测价值的冠状动脉供血不足的心电图标准(“近缺血”表现、J点压低4毫米及以上)不适用于女性;——静息时心电图异常而运动时变为正常的情况,无论男性还是女性,冠状动脉均正常;——假阳性发生率为22.9%,是男性的4倍;——普萘洛尔(口服60毫克)可使静息和运动心电图中的这些假缺血性改变恢复正常,提供了一种识别假阳性的简单方法。