Serradimigni A, Bory M, Djiane P, Sacerdote P, Leonetti J, Mathieu P, Lodovivi F, Cappuccio P, Egre A
Arch Mal Coeur Vaiss. 1976 Sep;69(9):951-8.
The authors have made a study of the fate of 118 patients with pulmonary embolism. The mortality (21.8%) is related not only to the embolus itself (especially to the recurrent types) but also to the condition of the affected area. Recurrence is common (34%), serious (9 deaths out of 25), and early (during the first three months.). No treatment or inadequate treatment are the main causes. Treatment works effectively on the pulmonary circulation, which becomes reestablished in the majority of cases, but it carries the risk of a high incidence of haemorrhage (29%) which is severe (2 deaths and 10 tranfusions of more than one litre of blood). In the long term, the prognosis is linked to the developments in the lower limbs, in which there is a progressive failure of venous drainage (46 cases out of 57), even in cases in which there was no local sign of phlebitis at the time of the original embolus.
作者对118例肺栓塞患者的转归进行了研究。死亡率（21.8%）不仅与栓子本身（尤其是复发性栓子类型）有关，还与受累区域的状况有关。复发很常见（34%），情况严重（25例中有9例死亡），且复发较早（在前三个月内）。未治疗或治疗不当是主要原因。治疗对肺循环有效，大多数情况下肺循环会重新建立，但存在出血发生率高（29%）的风险，其中严重出血（2例死亡，10例输血超过1升）。从长远来看，预后与下肢的病情发展有关，即使在最初发生栓子时没有局部静脉炎迹象的病例中，也会出现下肢静脉引流逐渐衰竭（57例中有46例）。
