Hassoux R, Croisille Y
C R Acad Hebd Seances Acad Sci D. 1976 Jul 12;283(2):183-5.
Among the cellular antigens, demonstrated by their reaction with Rabbit anti-embryonic Chick liver serum, two are present in the supernatant fraction obtained after ultracentrifugation of liver extracts from 6-day-old Chick embryos, and in the sedimentable fraction from the 9th day onward. A third antigen, detectable from the 9th day of incubation, is found only in the sedimentable fraction. The three antigens exist, but at much lower concentrations, in adult Chick kidney. Rabbit anti-embryonic Chick mesonephros serum permits the demonstration of at least one kidney-specific antigen. The latter, localized at the apical part of the cells of the proximal secretory tubules, is present in mesonephros and embryonic or adult metanephros. Although suggested by several observations, the presence of antibodies reacting with mesonephros-specific antigens could not be definitely established.
在细胞抗原中，通过它们与兔抗鸡胚肝血清的反应得以证实，其中两种抗原存在于6日龄鸡胚肝脏提取物超速离心后获得的上清液部分，从第9天起也存在于可沉淀部分。第三种抗原从孵化第9天开始可检测到，仅存在于可沉淀部分。这三种抗原在成年鸡肾中也存在，但浓度要低得多。兔抗鸡胚中肾血清可证实至少一种肾脏特异性抗原的存在。后者定位于近端分泌小管细胞的顶端部分，存在于中肾以及胚胎或成年后肾中。尽管有几项观察结果提示，但与中肾特异性抗原发生反应的抗体的存在尚未得到明确证实。
