Giaever I, Keese C R
School of Science, Rensselaer Polytechnic Institute, Troy, New York 12180-3590.
Nature. 1993 Dec 9;366(6455):591-2. doi: 10.1038/366591a0.
An electrical biosensor is described that can continuously track morphological changes of adherent cells providing quantitative data from both sparse and confluent cultures. The method is capable of detecting vertical motion of cells of the order of 1 nm, much below the resolution of an optical microscope.
本文描述了一种电化学生物传感器,它能够连续跟踪贴壁细胞的形态变化,为稀疏培养和汇合培养提供定量数据。该方法能够检测到约1纳米量级的细胞垂直运动,远低于光学显微镜的分辨率。