Cools A R, Rots N Y, Ellenbroek B, de Kloet E R
Department of Psycho- and Neuropharmacology, University of Nijmegen, The Netherlands.
Neuropsychobiology. 1993;28(1-2):100-5. doi: 10.1159/000119009.
An overview of the most important features of the two distinct types of individuals which normally co-occur in an unselected population of Wistar rats is given. It reveals that the overall make-up and reactivity of the brain, as well as the endocrinological and immunological systems differ completely between the two types of individuals. Each of these types of individuals has its own individual-specific hardware and software to cope with challenges from the internal or external environment, requires its own optimal niche, and is vulnerable for its own set of stressors.
本文概述了在未经过选择的Wistar大鼠群体中通常同时出现的两种不同类型个体的最重要特征。结果显示，这两种类型个体在大脑的整体构成和反应性以及内分泌和免疫系统方面完全不同。每一种类型的个体都有其自身特定的硬件和软件来应对来自内部或外部环境的挑战，需要其自身的最佳生态位，并且易受其自身特定的应激源影响。
