Citovsky V, Zambryski P
Department of Biochemistry and Cell Biology, State University of New York, Stony Brook 11794.
Annu Rev Microbiol. 1993;47:167-97. doi: 10.1146/annurev.mi.47.100193.001123.
Transport of nucleic acids through cell membranes is an essential biological process that occurs in all living organisms. This review focuses on two plant systems in which nucleic acid molecules are transported through membrane channels: transport of Agrobacterium T-DNA through nuclear pores and movement of plant viruses through intracellular connections. To provide a broader perspective, nuclear uptake of animal viruses and nuclear import/export of small nuclear (sn) RNA and messenger (m) RNA are described. By comparing the examined cases of nucleic acid transport, the review proposes a set of general rules for this type of transport through membrane channels.
核酸通过细胞膜的转运是所有生物体内都会发生的重要生物学过程。本综述聚焦于两个植物系统，其中核酸分子通过膜通道进行转运：根癌农杆菌T-DNA通过核孔的转运以及植物病毒通过细胞内连接的移动。为提供更广阔的视角，还描述了动物病毒的核摄取以及小核（sn）RNA和信使（m）RNA的核输入/输出。通过比较所研究的核酸转运实例，本综述提出了一套关于通过膜通道进行此类转运的一般规则。
